|Having freed himself from the Dead Zone, Garlic Jr. attacks Kami-sama's lookout with the help of four new underlings, trapping God and his assistant in a bottle. He uses this opportunity to release the Aquamist, a gas that basically turns anyone it reaches into a demon. Meanwhile, Gohan has snuck away from home with Haiya Dragon in order to visit his friends. Kuririn has a new girlfriend named Maron, and at the moment are with Buruma, Oolong, and the old man himself at Kame house. The Aquamist reaches the island, transforming them all into demons (With the exception of Kuririn and Maron, who were underwater when the mist passed over them). Gohan and his dragon manage to escape the effects as well.
Having now reached the island, Gohan finds himself attacked by his friends. Garlic Jr.'s minions arrive (which FUNimation has dubbed the Spice Boys), and inform Gohan of the Super Holy Water, the only thing that can counter the Aquamist. Piccolo comes to Gohan's rescue, but is bitten by one of the demons, and turns against our young hero as well.
Upon reaching Kami-sama's tower, Gohan meets Garlic Jr, who tells him how the Makyosei's (a red star) close approach to Earth freed him from the Dead Zone, and makes him stronger by the minute. Garlic Jr. orders his men to focus their attacks on Gohan, because it was him that banished the evil lord to the Dead Zone in the first place (although Kuririn still tries to help Gohan). Meanwhile, Vegeta is searching for Goku in deep space, hoping to keep up with his level of strength.
Piccolo begins to attack Gohan one on one, and does some serious damage to him. Kuririn, getting in the way of the battle, is bitten by Piccolo, and joins in against Gohan. It is at this moment that Piccolo steals the bottle containing Kami-sama and Popo from Garlic Jr. and releases them. Piccolo explains that since he is already a demon, the aquamist bite had no affect on him. Garlic Jr. becomes enraged, and the Makyosei approaches its apogee to Earth.
Knowing that there is no way to release the Super Holy Water before daybreak, Popo suggests that it be poured into the holes beneath Kami's palace where the winds would carry it around the world. However, on the way to this place rests the bodies of all the previous Kamis, known as the Shinsenkai. Any living Kami that attempts to pass through this area is in great danger. As the battle with Garlic Jr. and his minions continues on the surface, Kami is attacked by the previous gods, who drain his life force. Since Piccolo and Kami-sama are still spirtually linked, Piccolo begins to suffer in his battle. Despite the incredible amount of pain, Kami and Popo press on, finally reaching the bottom of the palace. With the dead gods busy attacking Kami, Popo manages to release the Super Holy Water, returning the Earth's population to normal.
Back on the surface, Gohan, Kuririn, and Piccolo continue to do battle with Garlic Jr, who becomes stronger every second. Gohan bores a hole into Garlic Jr.'s abdomen, but due to his wish of immortality, is resurrected on the spot. Finding out that the Aquamist has been countered by Kami, Garlic Jr. creates a new Dead Zone, hoping to suck the entire palace from its foundation. Gohan creates an energy shield around himself and his friends so that they will not be absorbed into the tear, but uses much of his energy maintaining it. Piccolo distracts Garlic Jr, allowing Gohan to destroy the Makyosei. With the evil star now gone, Garlic Jr. loses all of his power, and falls into the Dead Zone once again. With Garlic Jr. gone and peace once again restored, the Z warriors wonder where Goku could possibly be...